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Application field of diethyl malonate

Diethyl malonate is a colorless liquid with a sweet ether odor. It is a compound of the hydroxyl group in the two carboxyl groups of malonic acid, which is substituted by ethoxyl, and the molecular formula is CH2(COOC2H5)2. Diethyl malonate is influenced by two carbonyl groups and has high activity. It can produces sodium salt with sodium glycol, and then reacts with halogenated hydrocarbon to produce diethyl malonate, which is substituted for one or two alkyls.Diethyl malonate condensation reaction with carbonyl compounds, produce unsaturated compounds RCH = C (COOC2).Diethyl malonate can be used as raw material for medicine. Its other functions are as follows:
1.It is used as the intermediate of sulfonamide and barbiturate, as well as the intermediate of spices and dyes.
2. GB 2760 a 96 provides for the use of edible spices. Mainly used in the preparation of pear, apple, grape, cherry and other fruit flavors.
3. Diethyl malonate is an important intermediate for the preparation of 2-amino-4, 6-dimethoxypyrimidine, as well as the plasticizer 4 and diethyl malonate of nitric acid cellulose, which is an organic synthesis intermediate. Ethyl ester can be used for nitrification, and further the principle is to produce diethyl amine malonate, which is an important intermediate for synthesizing amino acids.
4. Check ammonia and potassium, for resin and nitrocellulose solvent, plasticizer.
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